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What Does an Elevated C3 Complement Mean? A C3 test measures certain proteins in your bloodstream that work with your immune system. There are nine of these proteins (C1-C9), but C3 and C4 are the most commonly measured. Changes in the levels of these proteins can be an early warning sign of an inflammatory process somewhere in the body.

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There are many different ways to investigate the 3-D structure of chromatin, such as 3C, 4C, 5C, and Hi-C. This article discusses the basic methodology and applications of the most commonly-used chromosome conformation capture-based assays, with a focus on Hi-C.

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Chromosome conformation capture techniques (often abbreviated to 3C technologies or 3C-based methods) are a set of molecular biology methods used to analyze the spatial organization of chromatin in a cell. These methods quantify the number of interactions between genomic loci that are nearby in 3-D space, but may be separated by many nucleotides in the linear genome.

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Not necessarily. While a high red blood cell count can indicate a disease or disorder, it doesn't always mean you have a health condition. Other factors — like living at a high altitude — can also have an impact on your red blood cell count. But, if you have a high red blood cell count, it's always a good idea to have additional testing ...

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The intricate folding of chromatin enables living organisms to store genomic material in an extremely small volume while facilitating proper cell function. Hi-C is a chromosome conformation capture (3C)-based technology to detect pair-wise chromatin interactions genome-wide, and has become a benchma …

Yet, there are huge problems with that. The liver is a wonderful machine at producing tons of C3 and C4 quickly as soon as it is used up in response to inflammation! That is why the vast majority of SLE patients have normal or high C3/C4 even during severe disease activity. The better test is to check for a CB-CAPS called EC4d.

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